Oscar-winning 1991 thriller A quiet of the Lambs is to be potted by the US Library of Congress as part of its National Film Registry.
The film - in which Sir Anthony Hopkins made his first entrance as serial killer Hannibal Lecter - was one of 25 new additions announced.
Others added Forrest Gump starring Tom Hanks, characteristic Disney animation Bambi and Charlie Chaplin's The Kid.
The titles were selected from 2,228 films chosen by the public.
Every new entrance must be measured "culturally, in the past or aesthetically" important in order to be added to the registry.
Other additions include the 1979 Sally Field film Norma Rae, Robert Rodriguez's 1992 debut mark El Mariachi and the 1953 report of War of the Worlds.
They are connected by such lesser-known titles as A Computer Animated Hand - a one-minute film made in 1972 that is one of the first examples of 3D computer animation.
The oldest additions are silent films dating from 1912. One documents the pre-World War I child labour reform movement, while the other is a farce beginning comic actor John Bunny.
Gump, which won Hanks his second Oscar for best actor in 1995, is the most latest of the new additions.
"These films are chosen because of their lasting significance to American culture," said James H Billington, who has been the US Congress librarian since 1987.
"Our film tradition must be secluded because these cinematic treasures document our history and culture and reproduce our hopes and dreams."